Allopregnanolone exerts persistent antidepressant effects by altering brain states

By | August 19, 2021
New research led by neuroscientists at Tufts University School of Medicine suggests the prolonged antidepressant effects of allopregnanolone, a neuroactive steroid used therapeutically to treat postpartum depression, may involve the ability of the compound to modify communication in an area of the brain important for mood and emotion regulation.