Framework for genomic surveillance of SARS-CoV-2 Mpro evolution

By | April 5, 2022
A recent study posted to the bioRxiv* preprint server investigated the active genetic evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro), its emerging mutations, and the existence of antiviral resistance against Mpro inhibitors like paxlovid.