Human LRRC15 protein is an inhibitory receptor for SARS-CoV-2 spike-mediated entry

By | November 30, 2021
In a recent study, published on the bioRxiv* preprint server, researchers identified human LRRC15 as an inhibitory receptor for SARS-CoV-2 entry, which directly binds to the receptor-binding domain (RBD) of the spike protein with a moderate affinity and inhibits spike-mediated entry.