Potent antibodies against SARS-CoV-2 can be produced without T follicular helper cells, suggests study

By | June 15, 2021
It has been uncertain whether antibodies produced via this non-canonical pathway are protective against SARS-CoV-2. In a new study, recently released as a preprint on the bioRxiv*server, the neutralization potency of these antibodies is compared with those traditionally produced in germinal center-based antiviral responses.