SARS-CoV-2-derived mutant peptides hamper T cells’ ability to recognize and destroy infected cells

By | March 5, 2021
A deep sequencing study of 747 SARS-CoV-2 virus isolates has revealed mutant peptides derived from the virus that cannot effectively bind to critical proteins on the surface of infected cells and, in turn, hamper activation of CD8+ killer T cells that recognize and destroy these infected cells.